The effects of Chlorella vulgaris on cardiovascular risk factors: A comprehensive review on putative molecular mechanisms.

Student Research Committee, Mashhad University of Medical Sciences, Mashhad, Iran; Department of Nutrition, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran. Department of Nutrition, Food Sciences and Clinical Biochemistry, School of Medicine, Social Determinants of Health Research Center, Gonabad University of Medical Science, Gonabad, Iran. Microbiology Research Group, College of Pharmacy, Al-Ayen University, Thi-Qar, Iraq. Medical Laboratory Technology Department, College of Medical Technology, The Islamic University, Najaf, Iraq. Biomedical Engineering Department, Al-Mustaqbal University College, 51001, Hillah, Iraq. Department of Pathobiology and Laboratory Sciences, North Khorasan University of Medical Sciences, Bojnurd, Iran. Department of Nutrition, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran. Department of Microbiology, School of Medicine, Infectious Diseases Research Center, Gonabad University of Medical Sciences, Gonabad, Iran. Department of Clinical Pharmacy, Faculty of Pharmacy, Kerman University of Medical Sciences, Kerman, Iran. Health Sciences Research Center, Torbat Heydariyeh University of Medical Sciences, Torbat Heydariyeh, Iran; School of Medical Sciences, Behbahan Faculty of Medical Sciences, Behbahan, Iran. Electronic address: NasehpahlavaniNE91@yahoo.com.

Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. 2023;:114624
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Abstract

High incidence rate of cardiovascular disease (CVD) make this condition as an important public health concern. The use of natural products in treating this chronic condition has increased in recent years one of which is the single-celled green alga Chlorella. Chlorella vulgaris (CV) has been studied for its potential benefits to human health due to its biological and pharmacological features. CV contains a variety of macro and micronutrients, including proteins, omega-3, polysaccharides, vitamins, and minerals. Some studies have indicated that taking CV as a dietary supplement can help reduce inflammation and oxidative stress. In some studies, cardiovascular risk factors that are based on hematological indices did not show these benefits, and no molecular mechanisms have been identified. This comprehensive review summarized the research on the cardio-protective benefits of chlorella supplementation and the underlying molecular processes.

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Publication Type : Review

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